Hi!
Uhmmm that is very weird. I have applications running DOTween even for a whole day, and never had this issue. Maybe you're not setting DOTween's timeScale, but you're instead changing Unity's timeScale (which would change the tweens timeScale too, unless they're set as timeScaleIndependent)?
Another thing might be that the phone somehow gets into "energy conservation" mode, but in that case you would see the framerate drop down, not the tweens getting slower, so I guess that's not it.
Let me know.
Cheers,
Daniele